Monte carlo simulation

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A simulation-optimization approach to integrate process design and planning decisions under technical and market uncertainties: A case from the chemical-pharmaceutical industry

C.M. Marques, S. Moniz, J.P. de Sousa, A.P. Barbosa-Póvoa

Computers and Chemical Engineering (Published)
Nov, 2017

This paper presents an innovative approach to solve the product-launch planning problem in the pharmaceutical industry, with uncertainty on the product demand and on clinical trials. A mixed integer linear programming (MILP) model, incorporating Monte Carlo simulation (MCS), was developed for…

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Optimization and Monte Carlo Simulation for Product Launch Planning under Uncertainty

C.M. Marques, S. Moniz, J.P. de Sousa, A.P. Barbosa-Póvoa

Computer Aided Chemical Engineering (Published)
Jan, 2016

This paper presents an innovative approach to solve the product-launch planning problem in the pharmaceutical industry, with uncertainty on the product demand and on clinical trials. A mixed integer linear programming (MILP) model, incorporating Monte Carlo simulation (MCS), was developed for…

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